White matter hyperintensities and changes in white matter integrity in patients with Alzheimer’s disease
نویسندگان
چکیده
منابع مشابه
White matter hyperintensities and normal-appearing white matter integrity in the aging brain
White matter hyperintensities (WMH) of presumed vascular origin are a common finding in brain magnetic resonance imaging of older individuals and contribute to cognitive and functional decline. It is unknown how WMH form, although white matter degeneration is characterized pathologically by demyelination, axonal loss, and rarefaction, often attributed to ischemia. Changes within normal-appearin...
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The targeted brain dysfunction that accompanies aging can have a devastating effect on cognitive and intellectual abilities. A significant proportion of older adults experience precipitous cognitive decline that negatively impacts functional activities. Such individuals meet clinical diagnostic criteria for dementia, which is commonly attributed to Alzheimer's disease (AD). Structural neuroimag...
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Case-control studies showed that migraine is associated with ischemic stroke. Studies assessing the prevalence of white matter lesions (WML) in migraine however, reported conflicting results, possibly attributable to selection bias by recruiting only severe cases. We conducted a population-based MRI study of migraineurs with aura (N=161), migraineurs without aura (N=134) and controls (N=140), 3...
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The severity of tissue changes associated with incidental white matter hyperintensities (WMH) in the elderly cannot be sufficiently determined by conventional MRI. We, therefore, performed a regional analysis of the magnetization transfer ratio (MTR) maps obtained on a 1.5 T scanner from 198 neurologically asymptomatic participants of the Austrian Stroke Prevention Study (mean age 70, age range...
متن کاملWhite matter MR hyperintensities in adult patients with congenital rubella.
PURPOSE To observe and quantify white matter hyperintensities on MR images in adults with schizophrenialike symptoms who had had congenital rubella, in order to elucidate the neuropathologic sequelae of this perinatal viral infection and to explore the potential relationship of these lesions to schizophrenia. METHODS Eleven deaf adult patients with documented prenatal rubella virus infection ...
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ژورنال
عنوان ژورنال: Neuroradiology
سال: 2010
ISSN: 0028-3940,1432-1920
DOI: 10.1007/s00234-010-0806-2